This study evaluated the psychobehavioral benefits of the Children’s Lives Include Moments of Bravery (CLIMB) intervention in 45 children (aged 6-11) with a parent/caregiver with cancer. Parent/caregiver reports of psychobehavioral functioning indicated signi-ficant decreases in children’s emotional symptoms and marginally significant reductions in conduct problems. Child reports of emotion regulation indicated significant increases in emotion awareness, significant decreases in emotion suppression, and nonsignificant increases in emotion-focused coping and dysregulated expression. Parents/caregivers and children reported high satisfaction with CLIMB. Results suggest CLIMB is a promising intervention for improving psychobehavioral functioning and emotion regulation in children with a parent/caregiver with cancer.